Antimicrobial and Biofilm Inhibiting Diketopiperazines

Antimicrobial and biofilm inhibiting diketopiperazines.

Diketopiperazines are the smallest cyclic peptides known. 90% of Gram-negative bacteria produce diketopiperazines and they have also been isolated from Gram-positive bacteria, fungi and higher organisms. Biosynthesis of cyclodipeptides can be achieved by dedicated nonribosomal peptide synthetases or by a novel type of synthetases named cyclopeptide synthases. Since the first report in 1924 a la...

Biofilm Formation, Antimicrobial Resistance and Biofilm-Related Genes among Uropathogens Isolated from Catheterized Uro-Oncology Patients

Background and Objective: Despite the critical importance of catheter as an indwelling medical device, its prolonged utilization in hospitalized patients may lead to infection. This study aimed to identify distribution of uropathogenic bacteria isolated from catheterized uro-oncology patients, their biofilm production, and antimicrobial resistance patterns to generally -used antibiotics. Mater...

Modeling biofilm antimicrobial resistance.

A computer model capable of integrating mechanisms of biofilm resistance to disinfection by antimicrobial agents was developed. Resistance mechanisms considered included retarded penetration due to a stoichiometric reaction between the antimicrobial agent and biomass, incomplete penetration due to a catalytic reaction between the antimicrobial agent and the biomass, and the existence of a fract...

Biofilm Formation and Antimicrobial Resistance in Enterococcus

Conclusive Notes on Biofilm and Antimicrobial Dressings.

72 The scientifi c symposium entitled The Role of Biofi lm in the Treatment of Chronic Ulcer, organized by the Croatian Academy of Medical Sciences with support from Stoma Medical has demonstrated its educational role. This issue of Acta Medica Croatica (AMC) brings current concepts on chronic venous disease (CVD), which should be acquired by physicians of various specialties, e.g., dermatovene...